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DOSE指数评分系统在慢性阻塞性肺疾病中的应用价值
海 冰1,2
1.(1)昆明医科大学第二附属医院呼吸内科二病区;2)泌尿外科三病区,云南 昆明 650101)
摘要:
[摘要]目的 探讨DOSE指数评分在慢性阻塞性肺疾病评价中的应用价值.方法 对122例稳定期COPD患者连续随访12 个月, 统计并记录患者的健康及生活情况.同时对COPD患者FEV1、DOSE进行评分,并记录COPD危险事件,包括呼吸衰竭和死亡、就诊次数、住院次数、总住院日, 门诊费用,住院费用,mMRC,年急性加重次数评分等.结果 122例COPD 稳定期患者DOSE 指数评分与FEV1%pred呈负相关(r=-0.73,P <0.05);与mMRC(r=085,P <0.01),急性加重次数(r=0.71,P <0.01),呼吸衰竭(r=0.65,P <0.01),心衰(r=0.50,P <0.01),门诊次数(r=0.12,P <0.01),住院次数(r=0.70,P <0.01),总住院日(r=0.66,P <0.01),门诊费用(r=0.13,P>0.05),住院费用(r=0.65,P<0.01)均呈正相关.ROC曲线分析记录COPD患者的DOSE指数的截断点和曲线面积. 结论 DOSE指数是一简单易行的COPD 评估工具, 与患者的预后及健康状况密切相关.
关键词:  [关键词]慢性阻塞性肺疾病  DOSE指数  预后
DOI:
分类号:
基金项目:[基金项目]云南省教育厅科学研究基金资助项目(2013C251)
Application value of DOSE Index Scoring System in Chronic Obstructive Pulmonary Disease
HAI Bing1,2
1.(1)The 2nd Ward,Dept. of Respiratory Medicine;2)The 3rd Wa rd,Dept. of Urology,The 2nd Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650101,China)
Abstract:
[Abstract]Objective To explore the application value of DOSE index score in the peitients with chronic obstructive pulmonary disease.Methods 122 cases of plateau COPD patients were followed up for 12 months, and we recorded and analyzed the patient's health and life. We also recorde FEV1 and DOSE scores of the patients with COPD,and record the COPD risk events,including the number of respiratory failure and death,and the times of hospitalization, total such confinement, outpatient expenses,hospitalization expenses,mMRC,and scored in the number of exacerbations,etc.Results The DOSE index score was negatively correlated with FEV1 % pred (r=0.73,P < 0.05) for 122 COPD patients, and were positively correlated with mMRC (r=085,P < 0.01),the annual number of exacerbations (r=0.71,P < 0.01), respiratory failure (r=0.65,P < 0.01), heart failure (r=0.50,P < 0.01), number of outpatient service (r=0.12,P<0.01), hospitalization time (r=0.70, P< 0.01), the total such confinement (r=0.66, P<0.01), outpatient expenses (r=0.13, P > 0.13), hospitalization expenses(r=0.65, P<0.01). ROC curve was used to analyzed the cut-off point and curve area of COPD DOSE index.Conclusion The DOSE index is a simple COPD assessment tools, and is closely related to the prognosis of patients and health.
Key words:  [Key words]Chronic obstructive pulmonary disease  DOSE index  Prognosis