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米力农治疗急性心肌梗死后心力衰竭的疗效观察
引用本文:景舒南,张小勇,卢静,杨芳,鲁一兵,杨婧.米力农治疗急性心肌梗死后心力衰竭的疗效观察[J].昆明医学院学报,2010,31(8):124-126.
作者姓名:景舒南  张小勇  卢静  杨芳  鲁一兵  杨婧
作者单位:昆明医学院附属延安医院心内科,云南心血管病医院,云南,昆明,650051
摘    要:目的探讨米力农治疗急性心肌梗死后心力衰竭的效果与安全性.方法 28例急性心肌梗死后出现心力衰竭的患者入院后接受米力农(剂量为0.375~0.75mg/(kg.d)治疗2~4d,治疗前后利用彩色多普勒心脏超声诊断仪评估患者的心功能.结果米力农治疗后患者的心指数和射血分数显著增加,分别为(2.3±0.5)vs(2.7±0.6)L/(min.m2)和(35±6)%vs(43±4)%,P〈0.05,未观察到严重的副反应的发生.结论米力农能有效地治疗急性心肌梗死后心力衰竭。

关 键 词:米力农  急性心肌梗死  心力衰竭

Therapeutic Effect of Milrinone on Heart Failure after Acute Myocardial Infarction
JING Shu-nan,ZHANG Xiao-yong,LU Jing,YANG Fang,LU Yi-bing,YANG Jing.Therapeutic Effect of Milrinone on Heart Failure after Acute Myocardial Infarction[J].Journal of Kunming Medical College,2010,31(8):124-126.
Authors:JING Shu-nan  ZHANG Xiao-yong  LU Jing  YANG Fang  LU Yi-bing  YANG Jing
Affiliation:(Dept. of Cardiology,The Affiliated Yan'an Hospital of Kunming Medical University,The Cardiovascular Diseases Hospital of Yunnan Province,Kunming Yunnan 650051,China)
Abstract:Objective To investigate the therapeutic effect and safety of milrinone in treatment of acute myocardial infarction(AM)I patients with severe heart failure.Methods Twenty-eight AMI patients with severe heart failure received intravenous milrinone therapy for 2~4 days 0.375~0.75 mg/(kg.d)].All patients' cardiac function was measured by echocardiography before and after the therapy.Results Compared with baseline values,the cardiac index and ejection fraction were significantly increased from 2.3±0.5 to 2.7±0.6L/(min.m2)(P〈0.05) and 35±6 to 43±4%(P〈0.05) respectively after milrinone therapy.No any severe side effects were observed.Conclusion Milrinone is effective and safe in treatment of AMI patients with severe heart failure.
Keywords:Milrinone  Acute myocardial infarction  Heart failure
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