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多发性骨髓瘤的治疗进展
张晓芸1,2
1.(1)曲靖市第二人民医院血液肿瘤科,云南 曲靖 655000;2)昆明医科大学第一附属医院血液科,云南省血液病研究中心,云南 昆明 650032)
摘要:
[摘要]多发性骨髓瘤是一种单克隆浆细胞恶性增殖性疾病,约占血液系统恶性肿瘤的10%.近年来,由于造血干细胞移植的开展,包含新药如沙利度胺、来那度胺和万珂等的联合化疗的应用,使得MM患者的平均生存期得到了明显的延长.应根据患者的临床症状、身体状况及预后,制定个体化的综合治疗策略.就多发性骨髓瘤患者的治疗策略进行综述.
关键词:  [关键词]多发性骨髓瘤  诱导治疗  干细胞移植  巩固治疗  维持治疗
DOI:
分类号:
基金项目:[基金项目]国家自然科学基金资助项目(81060046)
Advances in the Treatment of Multiple myeloma
ZHANG Xiao-yun1,2
1.(1)Dept. of The Blood Oncology,The 2nd People’s Hospital of Qujing,Qujing Yunnan 655000;2)Dept. of Hematology,The 1st Affiliated of Kunming Medical University/ Blood Disease Research Center of Yunnan Province,Kunming Yunnan 650000,China)
Abstract:
[Abstract]Multiple myeloma is a monoclonal plasma cell malignant proliferative disease,accounting for about 10% of malignant tumors of blood system. In recent years,due to the application of hematopoietic stem cell transplantation and the application of MDT by combining new drug such as thalidomide, lenalidomide and bortezomib,the average survival of MM patients was significantly longer than before. The treatment strategy should be individualized before treatment according to the patient's age,physical condition and complications .In this paper,the treatment strategy of multiple myeloma patients were reviewed.
Key words:  [Key words]Multiple myeloma  Induction therapy  Stem cell transplantation  Consolidation treatment  Maintenance treatment