| 摘要: |
| ［摘要］目的 探讨艾立舒在宫颈电环切除术（LEEP）治疗宫颈宫颈上皮内瘤变（CINⅡ~Ⅲ）合并HPV感染中的临床效果．方法 将165例CINⅡ~Ⅲ合并HPV感染行LEEP手术患者随机分为观察组83例和对照组82例．观察组术后即在宫颈创面推注艾立舒1支，术后第1天开始，每日阴道放置艾立舒2支，连续8 d；对照组术后常规用碘伏棉球擦洗宫颈创面换药．观察术后1周、2周、3周、4周阴道排液时间、出血率、宫颈创面修复及术后6个月宫颈HPV DNA感染情况等．结果 2组术后出血率、阴道排液时间、宫颈创面修复及HPV DNA比较，差异有统计学意义（P＜0.05）．结论 LEEP联合艾立舒治疗CINⅡ~Ⅲ合并HPV感染疗效确切． |
| 关键词: ［关键词］人乳头瘤病毒 上皮内瘤变 宫颈电环切除术 |
| DOI： |
| 分类号: |
| 基金项目:［基金项目］河北省科技基金资助项目 （20131075） |
|
| Clinical Effect of EaLeSu on CIN Ⅱ~Ⅲ Patients with HPV Infection Treated with LEEP |
|
HAN Rui-ying1,2
|
|
1.（1）Dept. of Gynaecology，The Affiliated Xingtai People’s Hospital of Hebei Medical University，Xingtai Hebei 054031;2）The Third Affiliated Hospital of Kunming Medical Univercity，Department Utrasound in Tumor Hospital of Yunnan Province，Kunming Yunnan 650018，China）
|
| Abstract: |
| ［Abstract］Objective To investigate the clinical effect of EaLeSu on cervical intraepithelial neoplasia （CIN Ⅱ~Ⅲ）patients with HPV infection treated with loop electrosurgical excision procedure （LEEP）. Methods 165 cases of CIN Ⅱ~Ⅲ patients with HPV infection who underwent LEEP operation were randomly divided into observation group （n＝83）and control group（n＝82）. In the observation group，patients were given a piece of EaLeSu in cervical wound at once in postoperative and two vaginal EaLeSu per day from the first postoperative day for eight consecutive days. The patients in the control group were treated with routine debridement and wound dressing with iodine. We observed the vaginal drainage times within 4 weeks after operative， bleeding rate， cervical wound repair， and cervical HPV DNA infection after 6 months. Results There were significant differences in the bleeding rate， vaginal drainage time， cervical wound repair and HPV DNA infection between the two groups（P < 0.05）. Conclusion EaLeSu showed a definite effect on cervical intraepithelial neoplasia（CIN Ⅱ~Ⅲ）patients with HPV infection treated with LEEP. |
| Key words: ［Key words］Human papillomavirus Intraepithelial neoplasia Loop electrosurgical excision procedure |